GATVita - Unlocking the Genetic Puzzle of Pregnancy Loss
Empower Your Medical Practice with GATVita
GATVita is a groundbreaking gene panel, meticulously designed by GATomics to help medical practitioners identify genetic factors contributing to recurrent pregnancy loss in their patients. By leveraging the robustness of Next-Generation Sequencing (NGS) and precision of AI-driven data analysis, GATVita offers clinicians an unprecedented understanding of the genetic basis underlying recurrent pregnancy loss.
Key Features of GATVita:
-
Comprehensive: Analyzes a broad range of genes linked to recurrent pregnancy loss.
-
Precise: Utilizes NGS and AI for accurate genetic interpretation.
-
Improved Patient Outcomes: Allows for early intervention and enhanced patient care.
-
User-Friendly: Delivers clear, actionable reports for physicians..
Key Genes and Associated Conditions in the GATVita Panel
​
-
MTHFR: Associated with Hyperhomocysteinemia and Neural Tube Defects, which could impact pregnancy outcomes.
-
RNF220: This gene is possibly involved in meiotic recombination, which is crucial for normal gamete formation.
-
MSH4: Mutations in this meiosis-specific protein could impact gametogenesis, potentially affecting fertility.
-
F3 and F5: Variations in these genes can lead to Thrombophilia, a clotting risk that can complicate pregnancy.
-
FSHR: Affects ovarian response to FSH in IVF, with potential implications for fertility treatment outcomes.
-
PROC: Associated with Protein C deficiency, another clotting risk that can complicate pregnancy.
-
MYLK: May affect uterine and vascular smooth muscle function, potentially influencing pregnancy outcomes.
-
FGB, FGA, FGG: These genes are associated with abnormal clotting, a risk factor for complications in pregnancy.
-
HTR1A: Mutations in the serotonin receptor could impact CNS and GI function, potentially affecting mood and digestion during pregnancy.
-
F12, F13A1, F2: Associated with clotting disorders (Factor XII deficiency, Factor XIII deficiency, Prothrombin thrombophilia), which can pose risks during pregnancy.
-
PRL: Abnormal Prolactin levels can impact fertility and pregnancy maintenance.
-
HLA-G: Key role in immunological tolerance in pregnancy, with variations potentially impacting pregnancy outcomes.
-
NEU1, GUSB, FKTN, ALAD, POMT1, ALDH18A1, CBS: These genes are associated with various rare genetic disorders that could potentially impact fetal development and pregnancy outcomes.
-
TSHR: Associated with Congenital hypothyroidism, a condition that can impact the development of the fetus.
-
FBLN5, UBE3A, FBN1, MYH11, NF1, INSR, RPS19, NLRP7: Variations in these genes can lead to a range of conditions that might indirectly affect pregnancy or the health of offspring.
-
SHOX, GATA1, FLNA, IKBKG, F8, SRY: These genes are involved in various syndromes and conditions that could affect fertility, fetal development, and pregnancy outcomes.
